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BMCBI
2010
13 years 8 months ago
2010
Background: Today, data evaluation has become a bottleneck in chromatographic science. Analytical instruments equipped with automated samplers yield large amounts of measurement d...
BMCBI
2008
13 years 8 months ago
2008
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
BMCBI
2007
13 years 8 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2008
13 years 8 months ago
2008
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
BMCBI
2007
13 years 8 months ago
2007
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...