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    BMCBI
    2007
    146views more  BMCBI 2007»
    PubMed related articles: a probabilistic topic-based model for content similarity
    13 years 10 months ago
    PubMed related articles: a probabilistic topic-based model for content similarity
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    Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
    Jimmy J. Lin, W. John Wilbur
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    BMCBI
    2007
    97views more  BMCBI 2007»
    Relating destabilizing regions to known functional sites in proteins
    13 years 10 months ago
    Relating destabilizing regions to known functional sites in proteins
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    Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
    Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
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    BMCBI
    2007
    113views more  BMCBI 2007»
    In silico panning for a non-competitive peptide inhibitor
    13 years 10 months ago
    In silico panning for a non-competitive peptide inhibitor
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    Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
    Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
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    BMCBI
    2008
    124views more  BMCBI 2008»
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
    13 years 10 months ago
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
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    Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
    Huanying Ge, Chao Cheng, Lei M. Li
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    BMCBI
    2008
    87views more  BMCBI 2008»
    Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
    13 years 10 months ago
    Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
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    Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
    Salim Bougouffa, Jim Warwicker
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