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PSB
2004
13 years 8 months ago
An Evidence Ontology for Use in Pathway/Genome Databases
An important emerging need in Model Organism Databases (MODs) and other bioinformatics databases (DBs) is that of capturing the scientific evidence that supports the information wi...
Peter D. Karp, Suzanne M. Paley, Cynthia J. Kriege...
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2010
165views more  BMCBI 2010»
13 years 7 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
ACMDIS
2010
ACM
13 years 7 months ago
The CLOTHO project: predicting application utility
When using the computer, each user has some notion that "these applications are important" at a given point in time. We term this subset of applications that the user va...
Joshua M. Hailpern, Nicholas Jitkoff, Joseph Subid...
GECCO
2010
Springer
186views Optimization» more  GECCO 2010»
13 years 8 months ago
Genetic rule extraction optimizing brier score
Most highly accurate predictive modeling techniques produce opaque models. When comprehensible models are required, rule extraction is sometimes used to generate a transparent mod...
Ulf Johansson, Rikard König, Lars Niklasson