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BMCBI
2008
13 years 7 months ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
BMCBI
2010
13 years 7 months ago
2010
Background: Biomedical research is set to greatly benefit from the use of semantic web technologies in the design of computational infrastructure. However, beyond well defined res...
BMCBI
2010
13 years 7 months ago
2010
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
BMCBI
2007
13 years 7 months ago
2007
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
BMCBI
2008
13 years 7 months ago
2008
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...