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BMCBI
2006
133views more  BMCBI 2006»
13 years 11 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
IANDC
2008
115views more  IANDC 2008»
13 years 11 months ago
Fair multi-party contract signing using private contract signatures
A multi-party contract signing protocol allows a set of participants to exchange messages with each other with a view to arriving in a state in which each of them has a pre-agreed...
Aybek Mukhamedov, Mark Dermot Ryan
BMCBI
2006
108views more  BMCBI 2006»
13 years 11 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal
BMCBI
2006
205views more  BMCBI 2006»
13 years 11 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
BMCBI
2006
103views more  BMCBI 2006»
13 years 11 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
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