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BMCBI
2008
111views more  BMCBI 2008»
13 years 11 months ago
GENOMEPOP: A program to simulate genomes in populations
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
Antonio Carvajal-Rodríguez
BMCBI
2008
135views more  BMCBI 2008»
13 years 11 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2007
143views more  BMCBI 2007»
13 years 11 months ago
An adaptive bin framework search method for a beta-sheet protein homopolymer model
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
Alena Shmygelska, Holger H. Hoos
BMCBI
2008
134views more  BMCBI 2008»
13 years 11 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
BMCBI
2008
123views more  BMCBI 2008»
13 years 11 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...