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» On the definition of role mining
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BMCBI
2010
118views more  BMCBI 2010»
13 years 10 months ago
Detecting lateral gene transfers by statistical reconciliation of phylogenetic forests
Background: To understand the evolutionary role of Lateral Gene Transfer (LGT), accurate methods are needed to identify transferred genes and infer their timing of acquisition. Ph...
Sophie S. Abby, Eric Tannier, Manolo Gouy, Vincent...
BMCBI
2008
110views more  BMCBI 2008»
13 years 10 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BMCBI
2007
86views more  BMCBI 2007»
13 years 10 months ago
Detecting microsatellites within genomes: significant variation among algorithms
Background: Microsatellites are short, tandemly-repeated DNA sequences which are widely distributed among genomes. Their structure, role and evolution can be analyzed based on exh...
Sébastien Leclercq, Eric Rivals, Philippe J...
BMCBI
2007
148views more  BMCBI 2007»
13 years 10 months ago
Evaluation of gene-expression clustering via mutual information distance measure
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...
Ido Priness, Oded Maimon, Irad E. Ben-Gal
BMCBI
2008
125views more  BMCBI 2008»
13 years 10 months ago
SynteBase/SynteView: a tool to visualize gene order conservation in prokaryotic genomes
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
Frédéric Lemoine, Bernard Labedan, O...