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BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
BMCBI
2008
119views more  BMCBI 2008»
13 years 7 months ago
A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
Background: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differe...
Sabine Pérès, Laurence Molina, Nicol...
COR
2010
123views more  COR 2010»
13 years 7 months ago
Decomposition, reformulation, and diving in university course timetabling
In many real-life optimisation problems, there are multiple interacting components in a solution. For example, different components might specify assignments to different kinds of...
Edmund K. Burke, Jakub Marecek, Andrew J. Parkes, ...
ALMOB
2006
109views more  ALMOB 2006»
13 years 7 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2006
144views more  BMCBI 2006»
13 years 7 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...