Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
Background: One of the important goals of microarray research is the identification of genes whose expression is considerably higher or lower in some tissues than in others. We wo...
Koji Kadota, Jiazhen Ye, Yuji Nakai, Tohru Terada,...
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...
Alexander F. Auch, Stefan R. Henz, Barbara R. Holl...
Background: Autoimmune diseases are disorders caused by an immune response directed against the body's own organs, tissues and cells. In practice more than 80 clinically dist...
Thomas Karopka, Juliane Fluck, Heinz-Theodor Mevis...