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BMCBI
2007
126views more  BMCBI 2007»
15 years 4 months ago
Multiple non-collinear TF-map alignments of promoter regions
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...
Enrique Blanco, Roderic Guigó, Xavier Messe...
BMCBI
2007
138views more  BMCBI 2007»
15 years 4 months ago
A systematic approach to detecting transcription factors in response to environmental stresses
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
BMCBI
2007
159views more  BMCBI 2007»
15 years 4 months ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...
BMCBI
2007
126views more  BMCBI 2007»
15 years 4 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2007
180views more  BMCBI 2007»
15 years 4 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
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