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159
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BMCBI
2004
15 years 3 months ago
2004
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
143
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BMCBI
2004
15 years 3 months ago
2004
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
145
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BMCBI
2004
15 years 3 months ago
2004
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
143
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BMCBI
2004
15 years 3 months ago
2004
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
179
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BMCBI
2004
15 years 3 months ago
2004
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...