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BMCBI
2004
13 years 11 months ago
2004
Background: Motivated by a biomedical database set up by our group, we aimed to develop a generic database front-end with embedded knowledge discovery and analysis features. A maj...
BMCBI
2004
13 years 11 months ago
2004
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
BMCBI
2004
13 years 11 months ago
2004
Background: Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease have pre...
BMCBI
2004
13 years 11 months ago
2004
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
BMCBI
2004
13 years 11 months ago
2004
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...