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BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
Amino acid classification based spectrum kernel fusion for protein subnuclear localization
Background: Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models...
Suyu Mei, Wang Fei
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...
BMCBI
2007
159views more  BMCBI 2007»
13 years 7 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...