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BIRD
2008
Springer
110views Bioinformatics» more  BIRD 2008»
13 years 10 months ago
SVM-Based Local Search for Gene Selection and Classification of Microarray Data
Abstract. This paper presents a SVM-based local search (SVM-LS) approach to the problem of gene selection and classification of microarray data. The proposed approach is highlighte...
Jose Crispin Hernandez Hernandez, Béatrice ...
BMCBI
2011
12 years 11 months ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson
BMCBI
2007
159views more  BMCBI 2007»
13 years 8 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...
BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate
ITA
2006
167views Communications» more  ITA 2006»
13 years 8 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino