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BMCBI
2007
148views more  BMCBI 2007»
13 years 8 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
EXACT
2009
13 years 5 months ago
Explaining a Result to the End-User: A Geometric Approach for Classification Problems
This paper addresses the issue of the explanation of the result given to the end-user by a classifier, when it is used as a decision support system. We consider machine learning cl...
Isabelle Alvarez, Sophie Martin
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
BMCBI
2010
132views more  BMCBI 2010»
13 years 8 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2008
134views more  BMCBI 2008»
13 years 8 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...