Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties, with potential implications ...
Alexander G. Churbanov, Carl Baribault, Stephen Wi...
For small samples, classi er design algorithms typically suffer from over tting. Given a set of features, a classi er must be designed and its error estimated. For small samples, ...
Seungchan Kim, Edward R. Dougherty, Junior Barrera...
Large amounts of protein-protein interaction data have been identified using various genome-scale screening techniques. Although interaction data is a valuable resource, high-thro...