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BMCBI
2010
131views more  BMCBI 2010»
13 years 8 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
BMCBI
2008
132views more  BMCBI 2008»
13 years 8 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
BMCBI
2007
98views more  BMCBI 2007»
13 years 8 months ago
Duration learning for analysis of nanopore ionic current blockades
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties, with potential implications ...
Alexander G. Churbanov, Carl Baribault, Stephen Wi...
JCB
2002
70views more  JCB 2002»
13 years 7 months ago
Strong Feature Sets from Small Samples
For small samples, classi er design algorithms typically suffer from over tting. Given a set of features, a classi er must be designed and its error estimated. For small samples, ...
Seungchan Kim, Edward R. Dougherty, Junior Barrera...
CSB
2005
IEEE
118views Bioinformatics» more  CSB 2005»
14 years 1 months ago
A Protein Interaction Verification System Based on a Neural Network Algorithm
Large amounts of protein-protein interaction data have been identified using various genome-scale screening techniques. Although interaction data is a valuable resource, high-thro...
Min Su Lee, Seung-Soo Park, Min Kyung Kim