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BMCBI
2006
125views more  BMCBI 2006»
13 years 8 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
BMCBI
2005
93views more  BMCBI 2005»
13 years 7 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2007
163views more  BMCBI 2007»
13 years 8 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...
BIBE
2007
IEEE
120views Bioinformatics» more  BIBE 2007»
13 years 12 months ago
Quality Assessment of Affymetrix GeneChip Data using the EM Algorithm and a Naive Bayes Classifier
Recent research has demonstrated the utility of using supervised classification systems for automatic identification of low quality microarray data. However, this approach requires...
Brian E. Howard, Beate Sick, Imara Perera, Yang Ju...