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BMCBI
2007
127views more  BMCBI 2007»
13 years 10 months ago
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
BMCBI
2007
136views more  BMCBI 2007»
13 years 10 months ago
Reduced modeling of signal transduction - a modular approach
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
Markus Koschorreck, Holger Conzelmann, Sybille Ebe...
BMCBI
2007
89views more  BMCBI 2007»
13 years 10 months ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
BMCBI
2008
169views more  BMCBI 2008»
13 years 10 months ago
MausDB: An open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects
Background: Large-scale, comprehensive and standardized high-throughput mouse phenotyping has been established as a tool of functional genome research by the German Mouse Clinic a...
Holger Maier, Christoph Lengger, Bruno Simic, Helm...
BMCBI
2008
155views more  BMCBI 2008»
13 years 10 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...