Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...