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BMCBI
2008
127views more  BMCBI 2008»
13 years 7 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
ISCI
2008
130views more  ISCI 2008»
13 years 7 months ago
Unified eigen analysis on multivariate Gaussian based estimation of distribution algorithms
Multivariate Gaussian models are widely adopted in continuous Estimation of Distribution Algorithms (EDAs), and covariance matrix plays the essential role in guiding the evolution...
Weishan Dong, Xin Yao
BIBM
2010
IEEE
158views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Protein-protein interaction prediction via Collective Matrix Factorization
Abstract--Protein-protein interactions (PPI) play an important role in cellular processes and metabolic processes within a cell. An important task is to determine the existence of ...
Qian Xu, Evan Wei Xiang, Qiang Yang
BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
FCT
2003
Springer
14 years 22 days ago
Graph Searching, Elimination Trees, and a Generalization of Bandwidth
The bandwidth minimization problem has a long history and a number of practical applications. In this paper we introduce a natural extension of bandwidth to partially ordered layo...
Fedor V. Fomin, Pinar Heggernes, Jan Arne Telle