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BMCBI
2010
13 years 7 months ago
2010
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
BMCBI
2007
13 years 7 months ago
2007
Background: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main...
BMCBI
2007
13 years 7 months ago
2007
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
BMCBI
2007
13 years 7 months ago
2007
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
BMCBI
2007
13 years 7 months ago
2007
Background: Biomedical ontologies are being widely used to annotate biological data in a computer-accessible, consistent and well-defined manner. However, due to their size and co...