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BMCBI
2008
107views more  BMCBI 2008»
15 years 4 months ago
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
Cong Zhou, Lucas D. Bowler, Jianfeng Feng
DATAMINE
2008
143views more  DATAMINE 2008»
15 years 4 months ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...
BC
2006
124views more  BC 2006»
15 years 4 months ago
Motor-maps, navigation and implicit space representation in the hippocampus
Abstract Multiple sensory-motor maps located in the brainstem and the cortex are involved in spatial orientation. Guiding movements of eyes, head, neck and arms they provide an app...
Alexander Kaske, Gösta Winberg, Joakim Cö...
BMCBI
2006
165views more  BMCBI 2006»
15 years 4 months ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
BMCBI
2007
113views more  BMCBI 2007»
15 years 4 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu