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BMCBI
2005
84views more  BMCBI 2005»
13 years 7 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
BMCBI
2006
75views more  BMCBI 2006»
13 years 7 months ago
Improving the specificity of high-throughput ortholog prediction
Background: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative g...
Debra L. Fulton, Yvonne Y. Li, Matthew R. Laird, B...
RECOMB
2004
Springer
14 years 8 months ago
The Statistical Significance of Max-Gap Clusters
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
Rose Hoberman, David Sankoff, Dannie Durand
BMCBI
2005
80views more  BMCBI 2005»
13 years 7 months ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
BMCBI
2004
150views more  BMCBI 2004»
13 years 7 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...