In the post-genomic era, the organization of genes into networks has played an important role in characterizing the functions of individual genes and the interplay between them. I...
Erliang Zeng, Giri Narasimhan, Lisa Schneper, Kala...
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
We present a novel framework to estimate protein-protein (PPI) and domain-domain (DDI) interactions based on a belief propagation estimation method that efficiently computes inter...
Faruck Morcos, Marcin Sikora, Mark S. Alber, Dale ...
Background: Non-coding RNAs gain more attention as their diverse roles in many cellular processes are discovered. At the same time, the need for efficient computational prediction...
Peter Raasch, Ulf Schmitz, Nadja Patenge, Julio Ve...
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...