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BMCBI
2007
87views more  BMCBI 2007»
13 years 10 months ago
'Unite and conquer': enhanced prediction of protein subcellular localization by integrating multiple specialized tools
Background: Knowing the subcellular location of proteins provides clues to their function as well as the interconnectivity of biological processes. Dozens of tools are available f...
Yao Qing Shen, Gertraud Burger
BMCBI
2007
157views more  BMCBI 2007»
13 years 10 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
BMCBI
2007
107views more  BMCBI 2007»
13 years 10 months ago
A general and efficient method for estimating continuous IBD functions for use in genome scans for QTL
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
Francois Besnier, Örjan Carlborg
BMCBI
2007
190views more  BMCBI 2007»
13 years 10 months ago
Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Emma Redhead, Timothy L. Bailey
BMCBI
2008
143views more  BMCBI 2008»
13 years 10 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
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