Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...
Background: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a ...
While much research has been done on finding similarities between protein sequences, there has not been the same progress on finding similarities between protein structures. Here ...
Tom Milledge, Gaolin Zheng, Tim Mullins, Giri Nara...