A function of a protein is dependent on its structure; therefore, predicting a protein structure from an amino acid sequence is an active area of research. Optimally predicting a ...
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
Genomics data has many properties that make it different from "typical" relational data. The presence of multi-valued attributes as well as the large number of null valu...
Amal Perera, Anne Denton, Pratap Kotala, William J...
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Conditional Random Fields (CRFs; Lafferty, McCallum, & Pereira, 2001) provide a flexible and powerful model for learning to assign labels to elements of sequences in such appl...
Thomas G. Dietterich, Adam Ashenfelter, Yaroslav B...