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» Optimizing Complex Loss Functions in Structured Prediction
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BMCBI
2007
124views more  BMCBI 2007»
13 years 9 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
CEC
2010
IEEE
13 years 10 months ago
A parallel framework for multi-objective evolutionary optimization
This work focuses on the development of a parallel framework method to improve the effectiveness and the efficiency of the obtained solutions by Multi-objective Evolutionary Algori...
Dipankar Dasgupta, David Camilo Becerra Romero, Al...
BMCBI
2010
136views more  BMCBI 2010»
13 years 9 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
ICASSP
2007
IEEE
14 years 3 months ago
Protein Fold Recognition using Residue-Based Alignments of Sequence and Secondary Structure
Protein structure prediction aims to determine the three-dimensional structure of proteins form their amino acid sequences. When a protein does not have similarity (homology) to a...
Zafer Aydin, Hakan Erdogan, Yucel Altunbasak
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 10 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...