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BMCBI
2008
13 years 10 months ago
2008
Background: Mining gene patterns that are common to multiple genomes is an important biological problem, which can lead us to novel biological insights. When family classification...
BMCBI
2008
13 years 10 months ago
2008
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
BMCBI
2008
13 years 10 months ago
2008
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
BMCBI
2008
13 years 10 months ago
2008
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
BMCBI
2008
13 years 10 months ago
2008
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...