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BMCBI
2011
13 years 5 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
BMCBI
2005
116views more  BMCBI 2005»
13 years 10 months ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
NECO
2008
108views more  NECO 2008»
13 years 10 months ago
Optimization of Decision Making in Multilayer Networks: The Role of Locus Coeruleus
Previous theoretical work has shown that a single layer neural network can implement the optimal decision process for simple, two alternative forced choice (2AFC) tasks. However, ...
Eric Shea-Brown, Mark S. Gilzenrat, Jonathan D. Co...
BMCBI
2004
323views more  BMCBI 2004»
13 years 10 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...