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» Overestimation for Multiple Sequence Alignment
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NAR
2007
109views more  NAR 2007»
13 years 7 months ago
GeneTrees: a phylogenomics resource for prokaryotes
The GeneTrees phylogenomics system pursues comparative genomic analyses from the perspective of gene phylogenies for individual genes. The GeneTrees project has the goal of provid...
Yuying Tian, Allan W. Dickerman
CSB
2003
IEEE
128views Bioinformatics» more  CSB 2003»
14 years 1 months ago
Degenerate Primer Design via Clustering
This paper describes a new strategy for designing degenerate primers for a given multiple alignment of amino acid sequences. Degenerate primers are useful for amplifying homologou...
Xintao Wei, David N. Kuhn, Giri Narasimhan
CISIS
2010
IEEE
14 years 2 months ago
Scalability Analysis of Progressive Alignment on a Multicore
—Sequence alignment is a fundamental instrument in Bioinformatics. In recent years, numerous proposals have been addressing the problem of accelerating this class of applications...
Sebastian Isaza, Friman Sánchez, Georgi Gay...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...