408 search results - page 72 / 82 » Overestimation for Multiple Sequence Alignment |
BMCBI
2007
13 years 7 months ago
2007
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
BMCBI
2007
13 years 7 months ago
2007
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
BMCBI
2011
13 years 2 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
BMCBI
2006
13 years 7 months ago
2006
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
CF
2007
ACM
13 years 11 months ago
2007
ACM
In the life sciences, genomic databases for sequence search have been growing exponentially in size. As a result, faster sequencesearch algorithms to search these databases contin...