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BMCBI
2010
13 years 7 months ago
2010
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
BMCBI
2010
13 years 7 months ago
2010
Background: Biological knowledge is represented in scientific literature that often describes the function of genes/ proteins (bioentities) in terms of their interactions (biointe...
BMCBI
2010
2010
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
13 years 7 months ago
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
BMCBI
2010
13 years 7 months ago
2010
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
BMCBI
2007
13 years 7 months ago
2007
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...