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BMCBI
2002
108views more  BMCBI 2002»
13 years 8 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
KDD
2010
ACM
217views Data Mining» more  KDD 2010»
13 years 7 months ago
Mining program workflow from interleaved traces
Successful software maintenance is becoming increasingly critical due to the increasing dependence of our society and economy on software systems. One key problem of software main...
Jian-Guang Lou, Qiang Fu, Shengqi Yang, Jiang Li, ...
JCC
2011
154views more  JCC 2011»
12 years 12 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
GIS
2006
ACM
14 years 10 months ago
Generalization of land cover maps by mixed integer programming
We present a novel method for the automatic generalization of land cover maps. A land cover map is composed of areas that collectively form a tessellation of the plane and each ar...
Jan-Henrik Haunert, Alexander Wolff
ICML
2002
IEEE
14 years 9 months ago
Learning the Kernel Matrix with Semi-Definite Programming
Kernel-based learning algorithms work by embedding the data into a Euclidean space, and then searching for linear relations among the embedded data points. The embedding is perfor...
Gert R. G. Lanckriet, Nello Cristianini, Peter L. ...