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» Parallel Computation in Biological Sequence Analysis
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BMCBI
2007
181views more  BMCBI 2007»
13 years 8 months ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park
CRV
2006
IEEE
92views Robotics» more  CRV 2006»
14 years 1 months ago
Simple Software for Microarray Image Analysis
A set of microarray images were acquired by a sequence of biological experiments which were scanned via a high resolution scanner. For each spot corresponding to a gene, the ratio...
Chaur-Chin Chen, Cheng-Yan Kao, Chun-Fan Chang, Hs...
BMCBI
2010
95views more  BMCBI 2010»
13 years 8 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
BMCBI
2004
131views more  BMCBI 2004»
13 years 7 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
CMSB
2008
Springer
13 years 9 months ago
Stochastic Analysis of Amino Acid Substitution in Protein Synthesis
Abstract. We present a formal analysis of amino acid replacement during mRNA translation. Building on an abstract stochastic model of arrival of tRNAs and their processing at the r...
Dragan Bosnacki, Huub M. M. ten Eikelder, M. N. St...