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BMCBI
2006
118views more  BMCBI 2006»
13 years 9 months ago
Exploration of biological network centralities with CentiBiN
Background: The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Central...
Björn H. Junker, Dirk Koschützki, Falk S...
BMCBI
2006
179views more  BMCBI 2006»
13 years 9 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
BMCBI
2006
127views more  BMCBI 2006»
13 years 9 months ago
PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens
Background: Here we describe PathogenMIPer, a software program for designing molecular inversion probe (MIP) oligonucleotides for use in pathogen identification and detection. The...
Sreedevi Thiyagarajan, Miloslav Karhanek, Michael ...
BMCBI
2005
104views more  BMCBI 2005»
13 years 9 months ago
Wildfire: distributed, Grid-enabled workflow construction and execution
Background: We observe two trends in bioinformatics: (i) analyses are increasing in complexity, often requiring several applications to be run as a workflow; and (ii) multiple CPU...
Francis Tang, Ching Lian Chua, Liang-Yoong Ho, Yun...
BMCBI
2002
137views more  BMCBI 2002»
13 years 9 months ago
ORFer - retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files
Background: Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite ...
Konrad Büssow, Steve Hoffmann, Volker Sievert