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» Parallelism in Gene Assembly
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CAINE
2008
13 years 8 months ago
Parallel Assembler for Fuzzy Genome Sequence Assembly
Assembly is an NP-Hard problem, which involves comparing fragments that have a time complexity of O(n2 ). This paper presents a parallel approach for sequence assembly. The parall...
Sara Nasser, Adrienne Breland, Frederick C. Harris...
FUIN
2008
96views more  FUIN 2008»
13 years 7 months ago
Computational Efficiency of Intermolecular Gene Assembly
In this paper, we investigate the computational efficiency of gene rearrangement operations found in ciliates, a type of unicellular organisms. We show how the so-called guided re...
Tseren-Onolt Ishdorj, Remco Loos, Ion Petre
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
On the origin and evolution of biosynthetic pathways: integrating microarray data with structure and organization of the Common
Background: The lysine, threonine, and methionine biosynthetic pathways share the three initial enzymatic steps, which are referred to as the Common Pathway (CP). In Escherichia c...
Marco Fondi, Matteo Brilli, Renato Fani
DNA
2001
Springer
125views Bioinformatics» more  DNA 2001»
13 years 12 months ago
PNA-mediated Whiplash PCR
The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
John A. Rose, Russell J. Deaton, Masami Hagiya, Ak...
DNA
2005
Springer
117views Bioinformatics» more  DNA 2005»
14 years 27 days ago
Simple Operations for Gene Assembly
Abstract. The intramolecular model for gene assembly in ciliates considers three operations, ld, hi, and dlad that can assemble any gene pattern through folding and recombination: ...
Tero Harju, Ion Petre, Vladimir Rogojin, Grzegorz ...