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BMCBI
2010
2010
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
13 years 7 months ago
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
BMCBI
2010
13 years 7 months ago
2010
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
BMCBI
2008
13 years 7 months ago
2008
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
BMCBI
2008
13 years 7 months ago
2008
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
BMCBI
2008
13 years 7 months ago
2008
Background: Feature selection is a pattern recognition approach to choose important variables according to some criteria in order to distinguish or explain certain phenomena (i.e....