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BMCBI
2010
111views more  BMCBI 2010»
13 years 8 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
232views more  BMCBI 2010»
13 years 8 months ago
LucidDraw: Efficiently visualizing complex biochemical networks within MATLAB
Background: Biochemical networks play an essential role in systems biology. Rapidly growing network data and e research activities call for convenient visualization tools to aid i...
Sheng He, Juan Mei, Guiyang Shi, Zhengxiang Wang, ...
BMCBI
2010
98views more  BMCBI 2010»
13 years 8 months ago
Learning to predict expression efficacy of vectors in recombinant protein production
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
Wen-Ching Chan, Po-Huang Liang, Yan-Ping Shih, Uen...
BMCBI
2007
88views more  BMCBI 2007»
13 years 8 months ago
Computational analysis of the relationship between allergenicity and digestibility of allergenic proteins in simulated gastric f
Background: Safety assessment of genetically modified (GM) food, with regard to allergenic potential of transgene-encoded xenoproteins, typically involves several different method...
Bingjun Jiang, Hong Qu, Yuanlei Hu, Ting Ni, Zhong...
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