115 search results - page 7 / 23 » Parameters for accurate genome alignment |
BMCBI
2010
13 years 7 months ago
2010
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
BMCBI
2008
13 years 7 months ago
2008
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
BMCBI
2008
13 years 7 months ago
2008
Background: While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation asses...
BMCBI
2007
13 years 7 months ago
2007
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
BMCBI
2010
13 years 7 months ago
2010
Background: Sequence alignment is one of the most important techniques to analyze biological systems. It is also true that the alignment is not complete and we have to develop it ...