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    BMCBI
    2010
    130views more  BMCBI 2010»
    A statistical approach to finding overlooked genetic associations
    13 years 8 months ago
    A statistical approach to finding overlooked genetic associations
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    Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
    Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
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    BMCBI
    2010
    167views more  BMCBI 2010»
    Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
    13 years 8 months ago
    Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
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    Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
    Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
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    BMCBI
    2010
    105views more  BMCBI 2010»
    Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
    13 years 8 months ago
    Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
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    Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
    Joel Hedlund, Hans Jörnvall, Bengt Persson
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    BMCBI
    2007
    97views more  BMCBI 2007»
    In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
    13 years 8 months ago
    In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
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    Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
    Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
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    BMCBI
    2008
    124views more  BMCBI 2008»
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
    13 years 8 months ago
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
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    Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
    Huanying Ge, Chao Cheng, Lei M. Li
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