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GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
14 years 28 days ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster
KELSI
2004
Springer
14 years 27 days ago
A Randomized Algorithm for Distance Matrix Calculations in Multiple Sequence Alignment
Multiple sequence alignment (MSA) is a vital problem in biology. Optimal alignment of multiple sequences becomes impractical even for a modest number of sequences [1] since the gen...
Sanguthevar Rajasekaran, Vishal Thapar, Hardik Dav...
JPDC
2007
167views more  JPDC 2007»
13 years 7 months ago
On the design of high-performance algorithms for aligning multiple protein sequences on mesh-based multiprocessor architectures
In this paper, we address the problem of multiple sequence alignment (MSA) for handling very large number of proteins sequences on mesh-based multiprocessor architectures. As the ...
Diana H. P. Low, Bharadwaj Veeravalli, David A. Ba...
GECCO
2006
Springer
171views Optimization» more  GECCO 2006»
13 years 11 months ago
A hybrid genetic search for multiple sequence alignment
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Seung-Hyun Moon, Sung-Soon Choi, Byung Ro Moon
WABI
2007
Springer
123views Bioinformatics» more  WABI 2007»
14 years 1 months ago
Inverse Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
Eagu Kim, John D. Kececioglu