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BMCBI
2010
132views more  BMCBI 2010»
13 years 9 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
BMCBI
2010
95views more  BMCBI 2010»
13 years 9 months ago
Quantifying the relationship between sequence and three-dimensional structure conservation in RNA
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
Emidio Capriotti, Marc A. Martí-Renom
BMCBI
2010
120views more  BMCBI 2010»
13 years 9 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...
BMCBI
2010
141views more  BMCBI 2010»
13 years 9 months ago
CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies
Background: Immunoglobulin (IG or antibody) and the T-cell receptor (TR) are pivotal proteins in the immune system of higher organisms. In cancer immunotherapy, the immune respons...
Yoji Nakamura, Tomoyoshi Komiyama, Motoki Furue, T...
BMCBI
2010
91views more  BMCBI 2010»
13 years 9 months ago
Algorithm-driven Artifacts in median polish summarization of Microarray data
Background: High-throughput measurement of transcript intensities using Affymetrix type oligonucleotide microarrays has produced a massive quantity of data during the last decade....
Federico M. Giorgi, Anthony M. Bolger, Marc Lohse,...