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» Pathway Analyst--Automated Metabolic Pathway Prediction
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IJBRA
2006
59views more  IJBRA 2006»
13 years 7 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
PSB
2004
13 years 8 months ago
An Evidence Ontology for Use in Pathway/Genome Databases
An important emerging need in Model Organism Databases (MODs) and other bioinformatics databases (DBs) is that of capturing the scientific evidence that supports the information wi...
Peter D. Karp, Suzanne M. Paley, Cynthia J. Kriege...
BMCBI
2006
145views more  BMCBI 2006»
13 years 7 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
NAR
2007
216views more  NAR 2007»
13 years 7 months ago
SYSTOMONAS - an integrated database for systems biology analysis of Pseudomonas
To provide an integrated bioinformatics platform for a systems biology approach to the biology of pseudomonads in infection and biotechnology the database SYSTOMONAS (SYSTems biol...
Claudia Choi, Richard Münch, Stefan Leupold, ...
CDC
2009
IEEE
141views Control Systems» more  CDC 2009»
13 years 5 months ago
Cell design in bacteria as a convex optimization problem
In this paper, we investigate the cell design of bacteria during the exponential growth. To this purpose, we propose to formulate the problem as a non differentiable convex optimiz...
Anne Goelzer, Vincent Fromion, Gérard Scorl...