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» Pattern Matching in Degenerate DNA RNA Sequences
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BMCBI
2005
179views more  BMCBI 2005»
13 years 7 months ago
MARS: Microarray analysis, retrieval, and storage system
Background: Microarray analysis has become a widely used technique for the study of geneexpression patterns on a genomic scale. As more and more laboratories are adopting microarr...
Michael Maurer, Robert Molidor, Alexander Sturn, J...
FCCM
2011
IEEE
311views VLSI» more  FCCM 2011»
12 years 11 months ago
String Matching in Hardware Using the FM-Index
—String matching is a ubiquitous problem that arises in a wide range of applications in computing, e.g., packet routing, intrusion detection, web querying, and genome analysis. D...
Edward Fernandez, Walid Najjar, Stefano Lonardi
RECOMB
2007
Springer
14 years 1 months ago
Nucleosome Occupancy Information Improves de novo Motif Discovery
A complete understanding of transcriptional regulatory processes in the cell requires identification of transcription factor binding sites on a genomewide scale. Unfortunately, th...
Leelavati Narlikar, Raluca Gordân, Alexander...
BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
BMCBI
2010
167views more  BMCBI 2010»
13 years 7 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...