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BMCBI
2008
105views more  BMCBI 2008»
13 years 7 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
Very Important Pool (VIP) genes - an application for microarray-based molecular signatures
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
BMCBI
2006
109views more  BMCBI 2006»
13 years 7 months ago
An integrated system for genetic analysis
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
BMCBI
2006
169views more  BMCBI 2006»
13 years 7 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
An approach for clustering gene expression data with error information
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
Brian Tjaden