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BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2007
97views more  BMCBI 2007»
13 years 8 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
VEE
2005
ACM
199views Virtualization» more  VEE 2005»
14 years 2 months ago
Escape analysis in the context of dynamic compilation and deoptimization
In object-oriented programming languages, an object is said to escape the method or thread in which it was created if it can also be accessed by other methods or threads. Knowing ...
Thomas Kotzmann, Hanspeter Mössenböck
HPCA
2011
IEEE
13 years 5 days ago
Beyond block I/O: Rethinking traditional storage primitives
Over the last twenty years the interfaces for accessing persistent storage within a computer system have remained essentially unchanged. Simply put, seek, read and write have deď¬...
Xiangyong Ouyang, David W. Nellans, Robert Wipfel,...
TC
2011
13 years 3 months ago
Maximizing Spare Utilization by Virtually Reorganizing Faulty Cache Lines
—Aggressive technology scaling to 45nm and below introduces serious reliability challenges to the design of microprocessors. Since a large fraction of chip area is devoted to on-...
Amin Ansari, Shantanu Gupta, Shuguang Feng, Scott ...