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    BMCBI
    2007
    99views more  BMCBI 2007»
    Towards validating the hypothesis of phylogenetic profiling
    13 years 11 months ago
    Towards validating the hypothesis of phylogenetic profiling
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    Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
    Raja Loganantharaj, Mazen Atwi
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    BMCBI
    2007
    115views more  BMCBI 2007»
    A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector
    13 years 11 months ago
    A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector
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    Background: Hidden Markov Models (HMMs) provide an excellent means for structure identification and feature extraction on stochastic sequential data. An HMM-with-Duration (HMMwD) ...
    Stephen Winters-Hilt, Carl Baribault
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    BMCBI
    2007
    217views more  BMCBI 2007»
    On consensus biomarker selection
    13 years 11 months ago
    On consensus biomarker selection
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    Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
    Janusz Dutkowski, Anna Gambin
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    BMCBI
    2007
    131views more  BMCBI 2007»
    An improved method for identifying functionally linked proteins using phylogenetic profiles
    13 years 11 months ago
    An improved method for identifying functionally linked proteins using phylogenetic profiles
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    Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
    Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
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    BMCBI
    2007
    115views more  BMCBI 2007»
    Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
    13 years 11 months ago
    Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
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    Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
    Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
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