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BMCBI
2010
119views more  BMCBI 2010»
13 years 7 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
BMCBI
2007
157views more  BMCBI 2007»
13 years 7 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
BMCBI
2007
131views more  BMCBI 2007»
13 years 7 months ago
Prediction of peptides observable by mass spectrometry applied at the experimental set level
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
William S. Sanders, Susan M. Bridges, Fiona M. McC...
BMCBI
2007
149views more  BMCBI 2007»
13 years 7 months ago
SAMPI: Protein Identification with Mass Spectra Alignments
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
Hans-Michael Kaltenbach, Andreas Wilke, Sebastian ...
EVOW
2007
Springer
14 years 1 months ago
Robust Peak Detection and Alignment of nanoLC-FT Mass Spectrometry Data
In liquid chromatography-mass spectrometry (LC-MS) based expression proteomics, samples from different groups are analyzed comparatively in order to detect differences that can p...
Marius C. Codrea, Connie R. Jimenez, Sander R. Pie...