—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
The FISH server is highly accurate in identifying the family membership of domains in a query protein sequence, even in the case of very low sequence identities to known homologue...